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Michael Friebe,

Otto-von-Guericke-University, Germany

Title: Conceptual idea for brain tumour treatment through intra-arterial pathways

Biography

Biography: Michael Friebe,

Abstract

There are many invasive (removal of the tumour tissuernthrough skull based access) and non-invasive medicalrntreatment strategies (mainly radiation therapy). Very oftenrnalso a combination of both.rnWe have created a new device, that would allow usingrnthe vascular structure as a possible pathway for treatingrnintracranial diseases. One option would be the placement ofrnradiation seeds directly into a brain tumour. The main issuesrnwith this catheter based approach are the defined puncture ofrnthe vessel, the prevention of liquid exchange (blood / brain),rnsealing of the vessel after the procedure, and the accuraternplacement and control of the procedure using externalrndiagnostic imaging.rnThe catheter based device (see figure), guided andrncontrolled by 3D X-ray (Artis Zeego, Siemens Healthcare,rnErlangen, Germany), is presented consisting of a one-sidedrntriple-hole balloon, a tube feeding this balloon and a secondrntube combined with a guide assistant for the puncture andrntreatment. 3D shaped X-ray markers allow accuraternplacement.rnThe presented pathway could be an alternative tumourrnaccess and particularly well suited for placements of smallrnradioactive seeds.